NeilMed Sinus Rinse 120 Premixed Sachets is a natural soothing saline nasal wash. A large volume low positive pressure nasal wash is the most effective way to irrigate the nose based on current medical studies. Nasal Irrigation is an excellent way to clean mucus from the nose making medication more effective. They also clean allergens, irritants, bacteria and viruses from the nose reducing the frequency of infection.